Ketamine
Common Names: Ketamine,
Special K, Cat Tranquilizer,
Chemical Name: 2-(2-chlorophenyl)-2-(methylamino)-cyclohexanone
[EroK 2015]
Classifications: Hallucinogen, Psychedelic,
Dissociative, Tranquilizer, Anesthetic, Analgesic
OUTLINE
(*C*) indicates a 90%+ Completed section
(SSS) indicates the section has been started
No prefix indicates the section hasn’t been started
-(SSS)Basic Introduction of the Drug
-Informs the reader of the general background of this drug, usually focusing on the current world
-(SSS)History of the Drug’s Use
-A brief guide to the history and use of the drug
-(SSS)Legal Status
-What is the legal availability of this drug?
-Testing your Drug and Handling your drug
-Doing an actual reagent test on your substance, taste testing, smell, sight, etc
-Ways to ensure the substance you have is the substance you want
-Handling your drug without harming the contents or losing potency
-Method of Ingestion
-How is this drug safely consumed or ingested?
-Central (Desired) Effects, Side Effects. What are the dosages?
-How much of the drug is needed for consumption
-What are some of the desirable effects of the drug?
-What are some undesirable effects?
-Long Term effects
Are there lingering long-lasting side effects
-Mechanism of Action – How does this Drug work in the body? [Physical (Physiological) and Mental (Psychological) effects]
-What are some of the physiological effects on the body?
-How does the drug affect the brain?
-Which neurotransmitters are impacted?
-Recommended Uses and Doses (Varies by person)
-Suggestions for how the drug could be used
-Addiction, Withdrawal, Tolerance
-Addiction profile of the drug. Is it physically or mentally addictive?
-What are the withdrawal effects?
-How does the tolerance of the substance impact the usage?
-Drug Combinations with this Drug (Mixing Drugs, USE CAUTION!)
-When mixing drugs, which combinations are most dangerous with this drug
-Enjoyable Drug Combinations
-(SSS)Medicinal Uses
-What has this drug been found to be beneficial for medicinally?
-Detection in Biological Fluids (Drug Testing)
-How can this drug be best detected in the body? For how long?
-(SSS)Personal Experiences
-Personal experience I have on the drug
-Friendly Experiences
-Experiences that close friends of mine have had on the drug
-Other notable experiences
-Experiences that others may have had on the drug, i.e. Sasha Shulgin, Terrence McKenna
-Useful Facts
-Are there any extra fun or useful facts about the drug that seem to be missing?
-Sources and Bibliography (Comments on sources)
-Sources of information on the drug.
(SSS) indicates the section has been started
No prefix indicates the section hasn’t been started
-(SSS)Basic Introduction of the Drug
-Informs the reader of the general background of this drug, usually focusing on the current world
-(SSS)History of the Drug’s Use
-A brief guide to the history and use of the drug
-(SSS)Legal Status
-What is the legal availability of this drug?
-Testing your Drug and Handling your drug
-Doing an actual reagent test on your substance, taste testing, smell, sight, etc
-Ways to ensure the substance you have is the substance you want
-Handling your drug without harming the contents or losing potency
-Method of Ingestion
-How is this drug safely consumed or ingested?
-Central (Desired) Effects, Side Effects. What are the dosages?
-How much of the drug is needed for consumption
-What are some of the desirable effects of the drug?
-What are some undesirable effects?
-Long Term effects
Are there lingering long-lasting side effects
-Mechanism of Action – How does this Drug work in the body? [Physical (Physiological) and Mental (Psychological) effects]
-What are some of the physiological effects on the body?
-How does the drug affect the brain?
-Which neurotransmitters are impacted?
-Recommended Uses and Doses (Varies by person)
-Suggestions for how the drug could be used
-Addiction, Withdrawal, Tolerance
-Addiction profile of the drug. Is it physically or mentally addictive?
-What are the withdrawal effects?
-How does the tolerance of the substance impact the usage?
-Drug Combinations with this Drug (Mixing Drugs, USE CAUTION!)
-When mixing drugs, which combinations are most dangerous with this drug
-Enjoyable Drug Combinations
-(SSS)Medicinal Uses
-What has this drug been found to be beneficial for medicinally?
-Detection in Biological Fluids (Drug Testing)
-How can this drug be best detected in the body? For how long?
-(SSS)Personal Experiences
-Personal experience I have on the drug
-Friendly Experiences
-Experiences that close friends of mine have had on the drug
-Other notable experiences
-Experiences that others may have had on the drug, i.e. Sasha Shulgin, Terrence McKenna
-Useful Facts
-Are there any extra fun or useful facts about the drug that seem to be missing?
-Sources and Bibliography (Comments on sources)
-Sources of information on the drug.
-Basic Introduction to Ketamine
Directly
from America’s Drug Enforcement Agency Factsheet: “Ketamine is a dissociative
anesthetic with some hallucinogenic effect” [DEAKet xxxx].
And
from Erowid.org, “Ketamine is a dissociative psychedelic used medically as a
veterinary and human anesthetic. It is one of the few addictive psychedelics…”
[EroK 2015].
For
those unfamiliar with the terminology of dissociative, psychedelic, and
hallucinogenic, please refer to the Classes
of Drugs page for an explicit definition.
Perceptions
of sight and sound are distorted, and the user may feel disconnected or not in
control. Ketamine may induce a state of sedation, feeling calm, relief from
pain, and amnesia. It is abused primarily for the ability to promote
dissociative sensations and hallucinogens [DEAKet xxxx].
Ketamine
is most often distributed in liquid or powder and occurs between friends at
raves, nightclubs, and private parties. Caucasian males between 17 and 25 are
the primary distributors of ketamine [IntKet 2004]. Produced commercially in a
number of countries including Germany, China, and the United States, production
of ketamine is a complex and time-consuming process making it impractical for a
clandestine procedure. This is why most of the ketamine distributed in the
United States is stolen or diverted from legitimate sources [IntKet 2004].
-History of Ketamine Usage
Ketamine has only been around since the
1960’s, where it was first synthesized by pharmacist Calvin Stevens in 1962 when
attempting to find a useful PCP replacement [EroK 2015] [Keta xxxx]. Ketamine
was used as a replacement for PCP since PCP would sometimes produce long
lasting hallucinogenic effects upon recovery from anesthesia. Psychotic
symptoms would sometimes ensue such as delusions, delirium, or psychosis [Keta
xxxx]. Further information on PCP is available on the PCP page.
Ketamine was patented in Belgium in 1963
and was later found to be a useful anaesthetic in 1965. In the late 1960’s
Ketamine was used as a field anesthetic by the U.S. during the Vietnam War.
Prescription Ketamine Hydrochloride was available under prescription under the
name Ketalar in 1969 [EroK 2015].
In the 1970’s recreational and
therapeutic usage of Ketamine had spread throughout the world. Ketamine has
been popularized in the world by the publication of two books describing
personal accounts of its usage. In 1981 the DEA filed official notice of its
intent to place Ketamine in Schedule III, but chose not to since the “incidence
of actual abuse was not sufficient to sustain the scheduling action.” However,
in 1999 the DEA declared the intent to schedule Ketamine and on 12 August 1999
Ketamine becomes federally illegal in the U.S [EroK 2015].
-Method of Ingestion
Ketamine
usually comes in clear liquid or white/off-white powder form, and so it can be
ingested several ways. Liquid ketamine can be injected or swallowed. Powdered
ketamine is most often a white powder and is usually ground finely into lines
for insufflations [IntKet 2004][DEAKet xxxx]. Although possible, Erowid.org
notes that ketamine is not often injected and more often snorted or insufflated
[EroK 2015].
-Central and Side Effects (Dosing part 1)
The
effects of ketamine vary greatly from individual to individual and are largely
dosage dependent. Common effects include amnesia, agitation, paralysis, memorly
loss, unconsciousness, nausea, and delirium. The onset is rapid and occurs
within a few minutes of administration [IntKet 2004]. Furthermore from the “Drug
Identification Bible” in 2001, intranasal ingestion, usually 10-60mg of pure
ketamine can produce mild hallucinations and last for about 30 minutes. Dosing
over 100mg can produce out-of-body, near death hallucinations; and terrors
[IntKet 2004].
With
this information, I ask myself why anyone would want to do a high dosage of
ketamine if it just produces near death hallucinations and terrors? Is there
some other attraction? Are the hallucinations very desirable at low doses?
Further research is needed
The
U.S. Department of Justice’s account of effect of ketamine seems to contrast
the central effects stated by Erowid.org which goes into detail about more
desirable effects of the drug. In the “Ketamine FAQ” section, low doses are
reported to show mild inebriation, dreamy thinking, stumbling, clumsy, “robotic”
movement, delayed sensations, increased sociability, and an interesting sense
of seeing the world differently [EroK 2015]. At higher doses, a fragmentation
of reality may occur. Users report a change in their environment or rapid
spinning. Some users report themselves as feeling removed from their surroundings
and their bodies. Some users describe the experience as “scary” [EroK 2015]
Get
TKenna’s opinion on Ketamine
-Mechanism of Action [Physical (Physiological) and Mental
(Psychological) effects]
-Sources
DEAKet
xxxx
Drug
Fact Sheet - Ketamine
http://www.dea.gov/druginfo/drug_data_sheets/Ketamine.pdf
Author:
DEA
IntKet
2004
Intelligence
Bulletin Ketamine
http://www.justice.gov/archive/ndic/pubs10/10255/10255p.pdf
Author:
US Department of Justice, Date Published: July 2004
EroK
2015
The
Vaults of Erowid - Ketamine
https://www.erowid.org/chemicals/ketamine/ketamine.shtml
Author:
Erowid, Date Initially Published: 1996, Updated: 10 Feb 2015
Keta
xxxx
History
of Ketamine
http://ketamine.com/history-of-ketamine/
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